A. severe B. generally C. treatment D. mistaken E. challenges F. disapprove G.

游客2023-10-26 47

问题 A. severe B. generally C. treatment D. mistaken E. challenges
F. disapprove G. matter H. rigorous I. magic J. suspected
K. publically L. factors M. faulty N. based O. questioned
Scientists have finally figured out how the key gene tied to obesity makes people fat, a major discovery that could open the door to an entirely new approach to the problem beyond diet and exercise.
Since 2007, researchers have known that a gene called FTO was related to obesity, but they didn’t know how, and could not tie it to appetite or other known【C1】______.
Now experiments reveal that a【C2】______ version of the gene causes energy from food to be stored as fat. Genetic tinkering in mice and on human cells in the lab suggests this can be reversed, giving hope that a drug or other【C3】______ might be developed to do the same in people.
The discovery【C4】______ the notion that "when people get obese it was basically their own choice because they choose to eat too much or not exercise," said study leader Melina Claussnitzer, a genetics specialist. For the first time, genetics has revealed a mechanism in obesity that was not really【C5】______ before and gives a third explanation or factor that’s involved.
Several obesity drugs are already on the market, but they are【C6】______ used for short-term weight loss and are aimed at the brain and appetite: they don’t directly target metabolism. Researchers can’t guess how long it might take before a drug【C7】______ on the new findings becomes available. But it’s unlikely it would be a【C8】______ pill that would enable people to eat anything they want without packing on the pounds. And targeting this fat pathway could affect other things, so a treatment would need【C9】______ testing to prove safe and effective.
The gene glitch doesn’t explain all obesity. It was found in 44 percent of Europeans but only 5 percent of blacks, so other genes clearly are at work, and food and exercise still【C10】______. [br] 【C2】

选项

答案 M

解析 (faulty)从词性判断，该空格需要填入形容词。选择faulty有两个依据：1．上文第一段对肥胖基因研究发现的论述，以及下文提及的genetic tinkering和this can be reversed，还有最后一段提及的gene glitch。从genetic tinkering(基因修复)、can be reversed(可以被逆转)和gene glitch(基因问题)推断，肥胖基因是出了问题的基因。2．与mistaken用法的辨析。mistaken仅仅用于表示观点、判断等是错误的，例如：Marijuana has few withdrawal effects，and this has given rise to the mistaken belief that it is not addictive．而faulty既可表示判断、论证等是错误的，又可表示机器、机制等出了故障和差错，例如：The report said the fire was started by faulty electrical wiring．

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